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Session 5

Dr. MK Bhan Memorial Session on

Bench to Bedside Research: Transnational and Basic Bio-Medical Sciences

This memorial session honors the legacy of Dr. M.K. Bhan, celebrating his pioneering contributions to biomedical sciences. The session will explore how scientific discoveries are translated into clinical applications, bridging the gap between lab research and patient care. Leading experts will share insights on advancing healthcare innovations and improving global health outcomes.

29 December 2024 10:30AM (IST)
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Featured Speakers

Meet our esteemed panel of experts who are at the forefront of advancing biomedical research and translating scientific discoveries into impactful healthcare innovations.

Khalid Shah

Dr. Khalid Shah​

Harvard Medical School
Boston, USA

Aamir Nazir

Dr. Aamir Nazir

CSIR-CDRI
Lucknow, INDIA

Dr. Hamid Matoo

Dr. Hamid Matoo

Sanofi
Cambridge, USA

Nadeem Shabir

Dr. Nadeem Shabir

SKUAST-K
Srinagar, India

Dr. Ajaz Ul Hamid​

Dr. Ajaz Ul Hamid

University of Kashmir
Srinagar, India

Tanzila Mukhtar

Dr. Tanzila Mukhtar

UC San Francisco
California, USA

Knowledge Lounge

      1. Sri Lanka stakeholder preferences for a new rotavirus vaccine candidate

      2. Rotavirus vaccination slows down a major childhood killer in Pakistan

      3. Gleason, Alec, Chirag K. Kumar, Eili Klein, Ramanan Laxminarayan, and Arindam Nandi. “Effect of rotavirus vaccination on the burden of rotavirus disease and associated antibiotic use in India: a dynamic agent-based simulation analysis.” Vaccine 42, no. 22 (2024): 126211.

      4. Mukhtar, Tanzila, Jeremie Breda, Manal A. Adam, Marcelo Boareto, Pascal Grobecker, Zahra Karimaddini, Alice Grison et al. “Temporal and sequential transcriptional dynamics define lineage shifts in corticogenesis.” The EMBO journal 41, no. 24 (2022): e111132.

      5. Mukhtar, Tanzila, and Verdon Taylor. “Untangling cortical complexity during development.” Journal of experimental neuroscience 12 (2018): 1179069518759332.

      6. Hameed R, Naseer A, Saxena A, Akbar M, Toppo P, Sarkar A, et al. Functional implications of NHR-210 enrichment in C. elegans cephalic sheath glia: insights into metabolic and mitochondrial disruptions in Parkinson’s disease models. Cell Mol Life Sci [Internet]. Springer International Publishing; 2024;81(1). Available from: https://doi.org/10.1007/s00018-024-05179-2

      7. Liu C, Shah K. Taming CAR T cell therapy toxicity. Nat Mater. Springer US; 2023;22(12):1444–5.

      8. Kanaya N, Kitamura Y, Vazquez ML, Franco A, Chen KS, van Schaik TA, et al. Gene-edited and -engineered stem cell platform drives immunotherapy for brain metastatic melanomas. Sci Transl Med. 2023;15(698).

      9. Chen KS, Reinshagen C, Van Schaik TA, Rossignoli F, Borges P, Mendonca NC, et al. Bifunctional cancer cell–based vaccine concomitantly drives direct tumor killing and antitumor immunity. Sci Transl Med. 2023;15(677).

      10. Mattoo H, Bangari DS, Cummings S, Humulock Z, Habiel D, Xu EY, et al. Molecular Features and Stages of Pulmonary Fibrosis Driven by Type 2 Inflammation. Am J Respir Cell Mol Biol. 2023;69(4):404–21.

      11. Gul I, Hassan A, Muneeb JM, Akram T, Haq E, Shah RA, et al. A multiepitope vaccine candidate against infectious bursal disease virus using immunoinformatics-based reverse vaccinology approach. Front Vet Sci. 2023;9.

      12. Akram T, Gul I, Parveez Zia M, Hassan A, Khatun A, Shah RA, et al. Ribavirin inhibits the replication of infectious bursal disease virus predominantly through depletion of cellular guanosine pool. Front Vet Sci. 2023;10(July):1–12.

      13. Sarkar A, Shamsuzzama, Kumar L, Hameed R, Nazir A. Multiple checkpoints of protein clearance machinery are modulated by a common microRNA, miR-4813-3p, through its putative target genes: Studies employing transgenic C. elegans model. Biochim Biophys Acta – Mol Cell Res [Internet]. Elsevier B.V.; 2022;1869(12):119342. Available from: https://doi.org/10.1016/j.bbamcr.2022.119342

      14. Liu L, Shah K. The Potential of the Gut Microbiome to Reshape the Cancer Therapy Paradigm: A Review. JAMA Oncol. 2022;8(7):1059–67.

      15. Ali R, Hameed R, Chauhan D, Sen S, Wahajuddin M, Nazir A, et al. Multiple Actions of H2S-Releasing Peptides in Human β-Amyloid Expressing C. elegans. ACS Chem Neurosci. 2022;13(23):3378–88.

      16. Kitamura Y, Kanaya N, Moleirinho S, Du W, Reinshagen C, Attia N, et al. Anti-EGFR VHH-armed death receptor ligand–engineered allogeneic stem cells have therapeutic efficacy in diverse brain metastatic breast cancers. Sci Adv. 2021;7(10):1–18.

      17. Mahajan VS, Mattoo H, Sun N, Viswanadham V, Yuen GJ, Allard-Chamard H, et al. B1a and B2 cells are characterized by distinct CpG modification states at DNMT3A-maintained enhancers. Nat Commun [Internet]. Springer US; 2021;12(1):1–17. Available from: http://dx.doi.org/10.1038/s41467-021-22458-9

      18. Khalsa JK, Cheng N, Keegan J, Chaudry A, Driver J, Bi WL, et al. Immune phenotyping of diverse syngeneic murine brain tumors identifies immunologically distinct types. Nat Commun [Internet]. Springer US; 2020;11(1). Available from: http://dx.doi.org/10.1038/s41467-020-17704-5

      19. Ali R, Pal HA, Hameed R, Nazir A, Verma S. Controlled release of hydrogen sulfide significantly reduces ROS stress and increases dopamine levels in transgenic: C. elegans. Chem Commun [Internet]. Royal Society of Chemistry; 2019;55(68):10142–5. Available from: http://dx.doi.org/10.1039/c9cc05153h

      20. Reinshagen C, Bhere D, Choi SH, Hutten S, Nesterenko I, Wakimoto H, et al. CRISPR-enhanced engineering of therapy-sensitive cancer cells for self-targeting of primary and metastatic tumors. Sci Transl Med. 2018;10(449):1–16.

      21. Shabir N, Khatun A, Nazki S, Gu S, Lee SM, Hur TY, et al. In vitro immune responses of porcine alveolar macrophages reflect host immune responses against porcine reproductive and respiratory syndrome viruses. BMC Vet Res. BMC Veterinary Research; 2018;14(1):1–13.

      22. Shamsuzzama, Kumar L, Nazir A. Modulation of alpha-synuclein expression and associated effects by microRNA let-7 in transgenic C. Elegans. Front Mol Neurosci. 2017;10(October):1–14.

      23. Du W, Seah I, Bougazzoul O, Choi GH, Meeth K, Bosenberg MW, et al. Stem cell-released oncolytic herpes simplex virus has therapeutic efficacy in brain metastatic melanomas. Proc Natl Acad Sci U S A. 2017;114(30):E6157–65.

      24. Robert Cronin Yung Peng, Rose Khavari ND, Kate Shannon . GODPJSJMCFRN. 乳鼠心肌提取 HHS Public Access. Physiol Behav. 2016;176(1):139–48.

      25. Mattoo H, Mahajan VS, Maehara T, Deshpande V, Della-Torre E, Wallace ZS, et al. Clonal expansion of CD4+ cytotoxic T lymphocytes in patients with IgG4-related disease. J Allergy Clin Immunol. 2016;138(3):825–38.

      26. Khatun A, Shabir N, Seo B-J, Kim B-S, Yoon K-J, Kim W-I. The Attenuation Phenotype of a Ribavirin-Resistant Porcine Reproductive and Respiratory Syndrome Virus Is Maintained during Sequential Passages in Pigs. J Virol. 2016;90(9):4454–68.

      27. Shabir N, Khatun A, Nazki S, Kim B, Choi EJ, Sun D, et al. Evaluation of the cross-protective efficacy of a chimeric porcine reproductive and respiratory syndrome virus constructed based on two field strains. Viruses. 2016;8(8):1–18.

      28. Sashidhara K V., Modukuri RK, Jadiya P, Rao KB, Sharma T, Haque R, et al. Discovery of 3-arylcoumarin-tetracyclic tacrine hybrids as multifunctional agents against Parkinson’s disease. ACS Med Chem Lett. 2014;5(10):1099–103.

      29. Van De Water JAJM, Bagci-Onder T, Agarwal AS, Wakimoto H, Roovers RC, Zhu Y, et al. Therapeutic stem cells expressing variants of EGFR-specific nanobodies have antitumor effects. Proc Natl Acad Sci U S A. 2012;109(41):16642–7.

      30. Kauer TM, Figueiredo JL, Hingtgen S, Shah K. Encapsulated therapeutic stem cells implanted in the tumor resection cavity induce cell death in gliomas. Nat Neurosci [Internet]. Nature Publishing Group; 2012;15(2):197–204. Available from: http://dx.doi.org/10.1038/nn.3019

      31. Squire LR. NIH Public Access. Neuron. 2009;61(1):1–7.

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